Kibron PLDscreen - features & benefits

Kibron PLDscreen is based on quantitative surface activity profiling of compounds by the high throughput Kibron Delta-8 analyzer, PLDnanosol reagent, software for data acquisition & analysis, and Kibron microtiter plates.

Basic features and benefits of the Kibron PLDscreen are:

compound classification by PLD index into four categories:

(1) very high, (2) high, (3) medium, and (4) low risk for PLD

compound consumption < 1 mg
throughput up to 1400 compounds / week, in full HTS mode, with automatic liquid handling system > 2000 compounds / week
easy integration to robotics and automatic liquid handling systems
comprehensive and intuitive software, immediate data read-out
standard 96-well platform
automatic sensor cleaning after each assay

Two software options are available: 1) PLDscreen standard software, dedicated only for PLD screening, and 2) PLDscreen PRO software, allowing additionally for physicochemical screening of Kaw, TSA, CMC and surface pKa.

The high throughput, small amount of material and minimal required manual labor allow a truly cost-efficient screening for phospholipidosis.

Performance in PLD screening

The Kibron PLDscreen offers high throughput PLD screening with minimal compound consumption, resulting in a fast and cost-efficient, yet highly accurate prediction of PLD.

PLDscreen comprises the Delta-8 high throughput analyzer, PLDnanosol reagent and Kibron microtiter plates.

Kibron Delta-8 analyzer